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Can I run Qwen3.5 122B-A10B (MoE) locally?

Alibaba · 125B parameters (10B active) · chat, reasoning, coding, vision.

Ollama weight files: Q4_K_M 81 GB (qwen3.5:122b).

Yes on 18 machines in this list. The smallest is Mac Studio M3 Ultra 96GB: Q4_K_M, about 83.7 GB, roughly 51 tokens per second, via Ollama. ollama run qwen3.5:122b

Setup on DGX Spark 128GB (NVIDIA, ASUS, Dell, Lenovo, HP, MSI, Acer, Gigabyte)

Open Qwen3.5 122B-A10B (MoE) in the checker

Hardware that fits

HardwareRuntimeQuantMemoryFitSpeedCommand
Mac Studio M3 Ultra 96GBOllamaQ4_K_M83.7 GBfits if the Mac GPU limit is raised~51 tok/sollama run qwen3.5:122b
Mac Studio M5 Ultra 96GBOllamaQ4_K_M83.7 GBfits if the Mac GPU limit is raised~74 tok/sollama run qwen3.5:122b
M3 Max 128GBOllamaQ4_K_M83.7 GBfits in fast memory~25 tok/sollama run qwen3.5:122b
M4 Max 128GBOllamaQ4_K_M83.7 GBfits in fast memory~34 tok/sollama run qwen3.5:122b
Mac Studio M4 Max (40c GPU) 128GBOllamaQ4_K_M83.7 GBfits in fast memory~34 tok/sollama run qwen3.5:122b
Mac Studio M5 Max (40c GPU) 128GBOllamaQ4_K_M83.7 GBfits in fast memory~38 tok/sollama run qwen3.5:122b
DGX Spark 128GB (NVIDIA, ASUS, Dell, Lenovo, HP, MSI, Acer, Gigabyte)OllamaQ4_K_M83.7 GBfits in fast memory~24 tok/sollama run qwen3.5:122b
M2 Ultra 192GBOllamaQ4_K_M83.7 GBfits in fast memory~49 tok/sollama run qwen3.5:122b
2x Mac Studio M5 Max (40c GPU) 128GBllama.cppQ8_0 GGUF132.6 GBfits in fast memory~20 tok/sllama-server -hf unsloth/Qwen3.5-122B-A10B-GGUF:Q8_0 --rpc node2:50052 -c 8192 # run rpc-server on each other node
Mac Studio M3 Ultra 256GBOllamaQ4_K_M83.7 GBfits in fast memory~51 tok/sollama run qwen3.5:122b
Mac Studio M5 Ultra (64c GPU) 256GBOllamaQ4_K_M83.7 GBfits in fast memory~74 tok/sollama run qwen3.5:122b
Mac Studio M5 Ultra (80c GPU) 256GBOllamaQ4_K_M83.7 GBfits in fast memory~74 tok/sollama run qwen3.5:122b
2x DGX Spark 128GBllama.cppQ8_0 GGUF132.6 GBfits in fast memory~13 tok/sllama-server -hf unsloth/Qwen3.5-122B-A10B-GGUF:Q8_0 --rpc node2:50052 -c 8192 # run rpc-server on each other node
4x Mac Studio M5 Max (40c GPU) 128GBllama.cppQ8_0 GGUF132.6 GBfits in fast memory~18 tok/sllama-server -hf unsloth/Qwen3.5-122B-A10B-GGUF:Q8_0 --rpc node2:50052,node3:50052,node4:50052 -c 8192 # run rpc-server on each other node
2x Mac Studio M5 Ultra (80c GPU) 256GBllama.cppQ8_0 GGUF132.6 GBfits in fast memory~39 tok/sllama-server -hf unsloth/Qwen3.5-122B-A10B-GGUF:Q8_0 --rpc node2:50052 -c 8192 # run rpc-server on each other node
Mac Studio M3 Ultra (80c GPU) 512GBOllamaQ4_K_M83.7 GBfits in fast memory~51 tok/sollama run qwen3.5:122b
4x DGX Spark 128GBllama.cppQ8_0 GGUF132.6 GBfits in fast memory~11 tok/sllama-server -hf unsloth/Qwen3.5-122B-A10B-GGUF:Q8_0 --rpc node2:50052,node3:50052,node4:50052 -c 8192 # run rpc-server on each other node
4x Mac Studio M5 Ultra (80c GPU) 256GBllama.cppQ8_0 GGUF132.6 GBfits in fast memory~35 tok/sllama-server -hf unsloth/Qwen3.5-122B-A10B-GGUF:Q8_0 --rpc node2:50052,node3:50052,node4:50052 -c 8192 # run rpc-server on each other node

Estimates, not benchmarks. Model sizes are ollama.com download sizes; memory needed adds headroom for ~8k tokens of context; speeds are rough figures from memory bandwidth. Data updated 2026-10-18.

A project by OnDevice Labs · llms.txt