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Can a RTX 5090 32GB run Qwen 2.5 72B?

No. Qwen 2.5 72B does not fit on RTX 5090 32GB: Q4_K_M needs 51.1 GB and 31.5 GB is usable.

Hardware: RTX 5090 32GB · Model: Qwen 2.5 72B

RTX 5090 32GB has 32 GB of VRAM and 1792 GB/s of memory bandwidth. The checker holds back 0.5 GB of VRAM for the driver and assumes 16 GB of system RAM, so fast memory usable by Ollama is 31.5 GB. Partial offload may also use 60% of that system RAM. Qwen 2.5 72B (72.7B, Alibaba) at Q4_K_M is a 47 GB download and needs 51.1 GB with headroom for about 8k tokens.

Best quantQ4_K_M
Download size47 GB
Memory needed51.1 GB
Usable fast memory31.5 GB
Fitdoes not fit
Estimated speedno estimate, it does not fit
Commandollama run qwen2.5:72b

Smallest hardware that runs it: M1 Max (32c GPU) 64GB at Q4_K_M (fits if the Mac GPU limit is raised, 51.1 GB needed, 48.0 GB usable, about 7 tok/s (estimate)). Can a M1 Max (32c GPU) 64GB run Qwen 2.5 72B?

A smaller Alibaba model that fits this hardware: Qwen3.5 35B-A3B (MoE) at Q4_K_M (fits in fast memory, 23.9 GB). Can a RTX 5090 32GB run Qwen3.5 35B-A3B (MoE)?

Open RTX 5090 32GB in the checker

Estimates, not benchmarks. Model sizes are ollama.com download sizes; memory needed adds headroom for ~8k tokens of context; speeds are rough figures from memory bandwidth. Data updated 2026-10-23.

A project by OnDevice Labs · llms.txt